Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730979 | 0.91 | HPGD (0.44) | MAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11852601 | 0.90 | ALOX15 (0.40) | ALDH1A1BCHEACHE | |
| SCHEMBL11730458 | 0.90 | ALDH1A1 (0.37) | MAPK1ALDH1A1TDP1CYSLTR2CYSLTR1 | |
| SCHEMBL11726911 | 0.90 | NPC1 (0.38) | MAPK1ALDH1A1TDP1CYSLTR2CYSLTR1 | |
| SCHEMBL11725477 | 0.90 | MAPK1 (0.46) | TSHRMAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11730056 | 0.90 | ALDH1A1 (0.41) | MAPK1ALDH1A1TDP1KDM4ECYSLTR2 | |
| SCHEMBL11730168 | 0.90 | TBXA2R (0.46) | MAPK1ALDH1A1TDP1KDM4E | |
| SCHEMBL11732457 | 0.90 | ALDH1A1 (0.39) | MAPK1ALDH1A1TDP1CYSLTR2CYSLTR1 | |
| SCHEMBL11730758 | 0.89 | TDP1 (0.45) | MAPK1ALDH1A1TDP1 | |
| SCHEMBL11733952 | 0.89 | ABCB1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |