Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.61 |
| ▸ | MMP12 | P39900 | 1/20 | 0.60 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.55 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.55 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.55 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332151 | 0.87 | FFAR1 (0.57) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL27602690 | 0.87 | PTPN1 (0.57) | FFAR1MMP12PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL117230 | 0.85 | FFAR1 (0.73) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL27689330 | 0.81 | FFAR4 (0.60) | FFAR1MMP12HDAC1HDAC8FFAR4 | |
| SCHEMBL23918813 | 0.81 | IAPP (0.53) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL1294972 | 0.81 | TAAR1 (0.58) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL408215 | 0.81 | PTPN1 (0.53) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5643123 | 0.80 | MMP12 (0.66) | FFAR1MMP12PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL1454387 | 0.79 | FFAR1 (0.60) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5642549 | 0.79 | CYP4F2 (0.51) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952275-B | Modulators for amyloid protein beta | HOFFMANN LA ROCHE | 2014-06-18 | — | — | CN | disclosed |
| CN-102164896-A | Phenethylamide derivatives and their heterocyclic analogues | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |
| CN-101952275-A | Modulators for amyloid beta | HOFFMANN LA ROCHE | 2011-01-19 | — | — | CN | disclosed |
| WO-2003076440-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS CALCITONIN AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-18 | — | — | WO | disclosed |