Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678705 | 0.83 | UGT2B7 (0.47) | KMT2AMEN1CYP1A2CYP2D6HIF1A | |
| SCHEMBL11704205 | 0.81 | AKR1B1 (0.62) | AKR1B1MAPK14KMT2AMEN1POLB | |
| SCHEMBL11704256 | 0.77 | AKR1B1 (0.58) | AKR1B1MAPK14CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL9765546 | 0.77 | AKR1B1 (0.69) | AKR1B1MAPK14KMT2AALDH1A1HPGD | |
| SCHEMBL11740509 | 0.77 | AKR1C3 (0.35) | AKR1B1KMT2AMEN1CYP2D6 | |
| SCHEMBL11600936 | 0.76 | AKR1B1 (0.68) | AKR1B1ALDH1A1HPGDMAPT | |
| SCHEMBL11707101 | 0.74 | AKR1B1 (0.66) | AKR1B1MAPK14KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL11708963 | 0.74 | AKR1B1 (0.66) | AKR1B1MAPK14KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL11693368 | 0.74 | AKR1B1 (0.58) | AKR1B1MAPK14CYP1A2CYP2D6ALDH1A1 | |
| Potassium Ion SCHEMBL11694910 | 0.74 | AKR1B1 (0.58) | AKR1B1MAPK14CYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051260-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | SYNTEX (U.S.A.) INC. (US) | 1977-09-27 | — | — | US | claimed |
| US-4051260-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | SYNTEX (U.S.A.) INC. (US) | 1977-09-27 | — | — | US | disclosed |
| US-3975540-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | SYNTEX (U.S.A.) INC. (US) | 1976-08-17 | — | — | US | disclosed |