Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17892066 | 0.84 | MEN1 (0.50) | UGT2B7MEN1KMT2AATMCYP2D6 | |
| SCHEMBL11723402 | 0.83 | AKR1B1 (0.55) | UGT2B7MEN1KMT2ACYP2D6CYP1A2 | |
| SCHEMBL27602362 | 0.82 | UGT2B7 (0.43) | UGT2B7MEN1KMT2AATMCYP2D6 | |
| SCHEMBL7653484 | 0.82 | UGT2B7 (0.47) | UGT2B7MEN1KMT2AATMCYP2D6 | |
| SCHEMBL30434655 | 0.82 | UGT2B7 (0.47) | UGT2B7MEN1KMT2AATMCYP2D6 | |
| SCHEMBL11741624 | 0.81 | AKR1C3 (0.57) | CYP1A2TSHRCYP2A6AKR1C3AKR1C2 | |
| SCHEMBL218804 | 0.77 | LMNA (0.46) | MEN1KMT2ACYP2D6 | |
| SCHEMBL3276260 | 0.77 | LMNA (0.46) | MEN1KMT2ACYP2D6 | |
| SCHEMBL13452609 | 0.77 | LMNA (0.46) | MEN1KMT2ACYP2D6 | |
| SCHEMBL30366336 | 0.76 | HDAC4 (0.42) | TSHRHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| CN-114349687-B | 3, 5-dicarboxylic ester-1, 4-dihydropyridine hydrogenation reagent, preparation method and application thereof | 中山奕安泰医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-114349685-B | 1, 4-dihydropyridine hydrogenation reagent, preparation method and application thereof | 中山奕安泰医药科技有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-114349686-B | 1, 4-dihydropyridine chiral hybrid hydrogenation reagent, preparation method and application thereof | 中山奕安泰医药科技有限公司 | 2023-07-07 | — | — | CN | disclosed |
| WO-2022077851-A1 | 1,4-DIHYDROPYRIDINE CHIRAL HYBRID HYDROGENATION REAGENT, PREPARATION METHOD AND APPLICATION THEREOF | 中山奕安泰医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |
| WO-2022077852-A1 | 3,5-DICARBOXYLIC ACID ESTER-1,4-DIHYDROPYRIDINE HYDROGENATING REAGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中山奕安泰医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |
| CN-114349687-A | 3, 5-dicarboxylic ester-1, 4-dihydropyridine hydrogenation reagent and preparation method and application thereof | 中山奕安泰医药科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114349686-A | 1, 4-dihydropyridine chiral hybrid hydrogenation reagent and preparation method and application thereof | 中山奕安泰医药科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114349685-A | 3, 5-diamide-1, 4-dihydropyridine hydrogenation reagent and preparation method and application thereof | 中山奕安泰医药科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | disclosed |