SCHEMBL11723966

SCHEMBL11723966

CC(Cl)Cc1nnc(N)s1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.50
POLB P06746 3/20 0.48
ALDH1A1 P00352 5/20 0.47
GLS O94925 2/20 0.44
F2 P00734 1/20 0.42
HTT P42858 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GAA P10253 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10130895 0.83 HPGD (0.53) HPGDPOLBALDH1A1GLSF2
SCHEMBL10954825 0.79 HPGD (0.50) HPGDPOLBALDH1A1GLSF2
SCHEMBL21085393 0.78 HPGD (0.49) HPGDPOLBALDH1A1GLSF2
SCHEMBL21085356 0.78 HPGD (0.49) HPGDPOLBALDH1A1GLSF2
SCHEMBL21085394 0.78 HPGD (0.49) HPGDPOLBALDH1A1GLSF2
SCHEMBL14977352 0.75 POLB (0.52) HPGDPOLBALDH1A1GLSF2
SCHEMBL26133606 0.74 HPGD (0.53) HPGDPOLBALDH1A1GLSF2
Chloroform SCHEMBL28257214 0.73 ALDH1A1 (0.61) HPGDPOLBALDH1A1GLSF2
SCHEMBL3902174 0.73 HPGD (0.45) HPGDPOLBALDH1A1GLSF2
SCHEMBL27875748 0.73 HPGD (0.45) HPGDPOLBALDH1A1GLSF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4053298-A HERBICIDAL COMPOSITIONS CONTAINING 1-THIADIAZOLYL-6-CARBAMOYLOXYTETRAHYDROPYRIMIDINONES AND METHODS THEREFOR VELSICOL CHEMICAL CORPORATION (US) 1977-10-11 US disclosed