Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719928 | 0.88 | KMT2A (0.51) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11721840 | 0.86 | HTT (0.54) | PTGS2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11725373 | 0.86 | MEN1 (0.53) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11723169 | 0.83 | ALOX5 (0.54) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11058028 | 0.82 | FLT1 (0.68) | FLT1FLT4KDRPHGDHMEN1 | |
| SCHEMBL11718597 | 0.80 | GAA (0.48) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11718691 | 0.79 | GAA (0.50) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11725136 | 0.77 | MAPT (0.54) | PTGS1PTGS2MEN1KMT2AMAPT | |
| SCHEMBL11726078 | 0.76 | MAPT (0.54) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11724015 | 0.76 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |