Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719928 | 0.88 | KMT2A (0.51) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL11718691 | 0.85 | GAA (0.50) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL11718597 | 0.82 | GAA (0.48) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL11724159 | 0.82 | THRB (0.47) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL31226590 | 0.81 | XDH (0.51) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL31226521 | 0.81 | GAA (0.50) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL1607866 | 0.80 | TP53 (0.55) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL940807 | 0.80 | TP53 (0.55) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL11725373 | 0.80 | MEN1 (0.53) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL11723199 | 0.80 | MAPT (0.50) | MAPTKMT2AMEN1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | claimed |
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |