SCHEMBL11724632

SCHEMBL11724632

CNC(=O)Oc1ccc(NS(=O)(=O)C2CCCCC2)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.44
ACHE P22303 1/20 0.39
PGAM1 P18669 1/20 0.39
FAAH O00519 2/20 0.38
EPHX1 P07099 1/20 0.38
ACLY P53396 1/20 0.38
MRGPRX1 Q96LB2 1/20 0.38
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
OPRK1 P41145 1/20 0.38
AXL P30530 1/20 0.38
MERTK Q12866 1/20 0.38
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11723641 0.94 MRGPRX1 (0.42) ACHEMRGPRX1SMN1; SMN2KDM4EHSD17B10
SCHEMBL11728054 0.82 ALDH1A1 (0.42) ACHESMN1; SMN2KDM4EHSD17B10
SCHEMBL11724899 0.78 KDM4E (0.57) ENPP3ENPP1SMN1; SMN2KDM4EHSD17B10
SCHEMBL11724512 0.77 CBX7 (0.42) BRD4ACHEMRGPRX1SMN1; SMN2KDM4E
SCHEMBL11721266 0.75 FFAR4 (0.39) ACHESMN1; SMN2KDM4E
SCHEMBL11720652 0.74 FFAR4 (0.60) MRGPRX1HSD17B10
SCHEMBL11720165 0.74 BRD4 (0.41) BRD4MRGPRX1SMN1; SMN2KDM4E
SCHEMBL11720685 0.74 KDM4E (0.48) ACHEKDM4EHSD17B10
SCHEMBL14513158 0.73 BRD4 (0.50) BRD4PGAM1ACLY
SCHEMBL11718627 0.72 MRGPRX1 (0.47) BRD4PGAM1MRGPRX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4051254-A SULFONAMIDO-AND AMIDOPHENYL N-METHYLCARBAMATES AND USE AS INSECTICIDES MOBIL OIL CORPORATION (US) 1977-09-27 US disclosed