Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724632 | 0.94 | BRD4 (0.44) | MRGPRX1ACHESMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11728054 | 0.85 | ALDH1A1 (0.42) | ACHESMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11724512 | 0.80 | CBX7 (0.42) | MRGPRX1ACHESMN1; SMN2MMP2MMP9 | |
| SCHEMBL11721266 | 0.78 | FFAR4 (0.39) | ACHESMN1; SMN2MMP2MMP9MMP14 | |
| SCHEMBL11720652 | 0.77 | FFAR4 (0.60) | MRGPRX1ALDH1A1HSD17B10 | |
| SCHEMBL11720165 | 0.77 | BRD4 (0.41) | MRGPRX1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11720685 | 0.76 | KDM4E (0.48) | ACHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11718627 | 0.75 | MRGPRX1 (0.47) | MRGPRX1 | |
| SCHEMBL12407120 | 0.74 | FKBP1A (0.53) | MRGPRX1ALDH1A1HRH1 | |
| SCHEMBL11720668 | 0.74 | ALDH1A1 (0.50) | ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051254-A | SULFONAMIDO-AND AMIDOPHENYL N-METHYLCARBAMATES AND USE AS INSECTICIDES | MOBIL OIL CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |