Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 3/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | RET | P07949 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672912 | 1.00 | EYA3 (0.66) | EYA3CYP2C19L3MBTL1APPCYP2C9 | |
| SCHEMBL11734608 | 0.89 | L3MBTL1 (0.64) | EYA3CYP2C19L3MBTL1CYP2C9SLC22A12 | |
| SCHEMBL11672355 | 0.89 | L3MBTL1 (0.64) | EYA3CYP2C19L3MBTL1CYP2C9SLC22A12 | |
| SCHEMBL11728862 | 0.88 | L3MBTL1 (0.57) | EYA3CYP2C19L3MBTL1APPCYP2C9 | |
| SCHEMBL11672638 | 0.88 | EYA3 (0.64) | EYA3CYP2C19L3MBTL1APPCYP2C9 | |
| SCHEMBL11673100 | 0.86 | L3MBTL1 (0.62) | EYA3CYP2C19L3MBTL1CYP2C9SLC22A12 | |
| SCHEMBL11729109 | 0.86 | L3MBTL1 (0.62) | EYA3CYP2C19L3MBTL1APPCYP2C9 | |
| SCHEMBL11730698 | 0.86 | L3MBTL1 (0.62) | EYA3CYP2C19L3MBTL1CYP2C9SLC22A12 | |
| SCHEMBL11671790 | 0.86 | L3MBTL1 (0.90) | CYP2C19L3MBTL1APPCYP2C9BCHE | |
| SCHEMBL11736681 | 0.86 | L3MBTL1 (0.90) | CYP2C19L3MBTL1APPCYP2C9BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |