Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | NPC1 | O15118 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728152 | 0.87 | RAB9A (0.66) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11728115 | 0.86 | MAPT (0.77) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11728419 | 0.81 | SMN1; SMN2 (0.58) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL6905520 | 0.81 | NPC1 (0.67) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11724128 | 0.78 | RAB9A (0.74) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL21858365 | 0.77 | RAB9A (0.75) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11725983 | 0.76 | RAB9A (0.79) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11724096 | 0.76 | RAB9A (0.74) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL25001241 | 0.76 | RAB9A (0.82) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL25001209 | 0.75 | RAB9A (1.00) | RAB9ANPC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046770-A | IMMUNE REGULANTS | ELI LILLY AND COMPANY (US) | 1977-09-06 | — | — | US | disclosed |