Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | RAB9A | P51151 | 7/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.77 |
| ▸ | NPC1 | O15118 | 6/20 | 0.77 |
| ▸ | MEN1 | O00255 | 6/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.74 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.74 |
| ▸ | RELA | Q04206 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.74 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.63 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724128 | 0.92 | RAB9A (0.74) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL11725983 | 0.88 | RAB9A (0.79) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL6231579 | 0.87 | MAPT (1.00) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL11724340 | 0.86 | KMT2A (0.77) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL11725599 | 0.86 | RAB9A (0.60) | MAPTRAB9AKMT2ANPC1MEN1 | |
| Frentizole SCHEMBL599582 | 0.85 | RAB9A (1.00) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL11724096 | 0.85 | RAB9A (0.74) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL11729251 | 0.84 | KMT2A (0.73) | MAPTRAB9AKMT2ANPC1MEN1 | |
| Frentizole SCHEMBL11433152 | 0.84 | RAB9A (0.98) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL11728152 | 0.84 | RAB9A (0.66) | MAPTRAB9AKMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046770-A | IMMUNE REGULANTS | ELI LILLY AND COMPANY (US) | 1977-09-06 | — | — | US | claimed |
| US-4046770-A | IMMUNE REGULANTS | ELI LILLY AND COMPANY (US) | 1977-09-06 | — | — | US | disclosed |