Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29116803 | 0.88 | TDP1 (0.50) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL11724825 | 0.85 | TDP1 (0.43) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL22897579 | 0.83 | TDP1 (0.45) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL23615909 | 0.83 | TDP1 (0.45) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL29559533 | 0.80 | TDP1 (0.42) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL22897852 | 0.80 | TDP1 (0.42) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL22897938 | 0.79 | SLC6A4 (0.44) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL18579434 | 0.79 | ALDH1A1 (0.50) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL11721444 | 0.78 | SMN1; SMN2 (0.43) | TDP1CYP3A4ALOX15TP53SMN1; SMN2 | |
| SCHEMBL22897759 | 0.77 | SLC6A4 (0.40) | TDP1CYP3A4ALOX15TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035375-A | N-Substituted amino pyridines and derivatives thereof | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1977-07-12 | — | — | US | disclosed |
| US-3985756-A | Process for producing azasulfonium salts and rearrangement thereof to thio-ethers | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-10-12 | — | — | US | disclosed |