Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29559533 | 1.00 | TDP1 (0.42) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL29116803 | 0.87 | TDP1 (0.50) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL22897579 | 0.85 | TDP1 (0.45) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL22897938 | 0.84 | SLC6A4 (0.44) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL2129800 | 0.84 | MAPT (0.51) | TDP1CYP3A4TP53ALDH1A1KDM4E | |
| SCHEMBL23615909 | 0.81 | TDP1 (0.45) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL9069297 | 0.81 | ALDH1A1 (0.42) | TDP1CYP3A4TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL22897756 | 0.80 | SLC6A4 (0.41) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL29559393 | 0.80 | SLC6A4 (0.41) | TDP1CYP3A4ALOX15TP53THRB | |
| SCHEMBL11725792 | 0.80 | TDP1 (0.43) | TDP1CYP3A4ALOX15TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011722-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2021-01-21 | — | — | WO | disclosed |