Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 3/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735865 | 0.84 | ESR1 (0.45) | HDAC2HDAC8MEN1KMT2ALMNA | |
| SCHEMBL11732171 | 0.83 | FFAR1 (0.46) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL11732139 | 0.83 | FFAR1 (0.46) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL11730482 | 0.82 | KEAP1 (0.53) | FFAR1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL11727089 | 0.82 | PYGL (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL11160806 | 0.81 | MAPT (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4PDPK1 | |
| SCHEMBL9662545 | 0.80 | MCL1 (0.45) | PLAAT3PLAAT5PLAAT2PLAAT4LMNA | |
| SCHEMBL11728918 | 0.79 | F2RL1 (0.57) | FFAR1MEN1KMT2A | |
| SCHEMBL11729107 | 0.78 | TSHR (0.51) | MEN1KMT2A | |
| SCHEMBL11730029 | 0.77 | IAPP (0.53) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003936-A | HYPOTENSIVE AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1977-01-18 | — | — | US | claimed |
| US-4003936-A | HYPOTENSIVE AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1977-01-18 | — | — | US | disclosed |