Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453745 | 0.86 | NPC1 (0.72) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL11729473 | 0.83 | NPC1 (0.67) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL11837121 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL11729598 | 0.80 | RAB9A (0.80) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL11829327 | 0.80 | ALDH1A1 (0.56) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL11730716 | 0.78 | ALDH1A1 (0.53) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL11824435 | 0.78 | HPGD (0.63) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL14637696 | 0.77 | RAB9A (1.00) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL29764989 | 0.77 | RAB9A (1.00) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL2749120 | 0.77 | ALDH1A1 (0.69) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006239-A | Benzoic acid amides for mycobacterium infections | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | claimed |