Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11787743 | 0.88 | RAB9A (0.63) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL9397355 | 0.88 | RAB9A (0.76) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL11729328 | 0.87 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL11732577 | 0.87 | RAB9A (0.79) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL11785004 | 0.85 | RAB9A (0.67) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL11787516 | 0.83 | RAB9A (0.70) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL11732116 | 0.83 | GAA (0.53) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL11731952 | 0.82 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL11789137 | 0.81 | RAB9A (0.55) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL11794415 | 0.81 | GAA (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002751-A | SLEEP INDUCERS, CNS DEPRESSANTS | SANDOZ, INC. (US) | 1977-01-11 | — | — | US | disclosed |