Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.67 |
| ▸ | NPBWR1 | P48145 | 14/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11787743 | 0.86 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1S1PR4 | |
| SCHEMBL11732577 | 0.85 | RAB9A (0.79) | RAB9ANPC1SMN1; SMN2ALDH1A1S1PR4 | |
| SCHEMBL11726417 | 0.83 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2ALDH1A1S1PR4 | |
| SCHEMBL11731952 | 0.81 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1S1PR4 | |
| SCHEMBL11728795 | 0.80 | SMN1; SMN2 (1.00) | RAB9ANPC1SMN1; SMN2ALDH1A1S1PR4 | |
| SCHEMBL11789137 | 0.80 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1S1PR4 | |
| SCHEMBL11729328 | 0.77 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1S1PR4 | |
| SCHEMBL11785004 | 0.75 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2ALDH1A1S1PR4 | |
| SCHEMBL11730721 | 0.74 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1S1PR4 | |
| SCHEMBL11794415 | 0.74 | GAA (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002751-A | SLEEP INDUCERS, CNS DEPRESSANTS | SANDOZ, INC. (US) | 1977-01-11 | — | — | US | disclosed |