Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | PTGFR | P43088 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733944 | 0.89 | KMT2A (0.42) | MEN1KMT2ATAAR1ABCB1ATM | |
| SCHEMBL11726284 | 0.89 | TBXA2R (0.45) | ABCB1TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11735554 | 0.89 | PTGFR (0.45) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11728921 | 0.89 | ADRB2 (0.46) | KMT2ATBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11850224 | 0.88 | PTGFR (0.57) | KMT2ATBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11730097 | 0.87 | TBXA2R (0.51) | MEN1KMT2ATBXA2RPTGER1PTGFR | |
| SCHEMBL11726066 | 0.87 | PTGFR (0.44) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11849657 | 0.87 | TBXA2R (0.44) | KMT2ATBXA2RPTGER1PTGFRPTGER3 | |
| Water SCHEMBL11730250 | 0.87 | PTGFR (0.56) | KMT2ATBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11728034 | 0.87 | TBXA2R (0.47) | KMT2ATBXA2RPTGER1PTGFRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |