Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
| ▸ | PTGFR | P43088 | 2/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725291 | 0.90 | TBXAS1 (0.43) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11729918 | 0.90 | LMNA (0.44) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11850224 | 0.90 | PTGFR (0.57) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11729965 | 0.89 | TBXAS1 (0.50) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11728921 | 0.89 | ADRB2 (0.46) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11728034 | 0.89 | TBXA2R (0.47) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11726284 | 0.89 | TBXA2R (0.45) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11735554 | 0.89 | PTGFR (0.45) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| Water SCHEMBL11730250 | 0.89 | PTGFR (0.56) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11730754 | 0.88 | LTA4H (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | claimed |
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |