Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12180309 | 0.83 | LMNA (0.49) | KDM4EHTTL3MBTL1LMNA | |
| SCHEMBL960631 | 0.81 | ALDH1A1 (0.39) | MAPTKDM4ERAD52ALDH1A1POLB | |
| SCHEMBL11723860 | 0.76 | CDK4 (0.44) | KDM4EALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2268882 | 0.74 | HTT (0.50) | KDM4EALDH1A1HTTL3MBTL1LMNA | |
| SCHEMBL19814656 | 0.74 | MAPT (0.44) | MAPTKDM4ERAD52ALDH1A1POLB | |
| SCHEMBL20278384 | 0.72 | MAPT (0.46) | MAPTKDM4ERAD52ALDH1A1POLB | |
| SCHEMBL3758184 | 0.72 | NPC1 (0.44) | MAPTKDM4EALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL19814290 | 0.71 | MAPT (0.44) | MAPTKDM4ERAD52ALDH1A1POLB | |
| SCHEMBL3691501 | 0.70 | HSP90AA1 (0.48) | MAPTKDM4EALDH1A1POLBHTT | |
| SCHEMBL17292935 | 0.70 | MAPT (0.44) | MAPTKDM4ERAD52ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060531-A | OPTICAL BRIGTENERS | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1977-11-29 | — | — | US | disclosed |