SCHEMBL11728645

SCHEMBL11728645

CCN(CCN(C)C)c1ccccc1OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 5/20 0.46
ESR1 P03372 1/20 0.42
ALDH1A1 P00352 3/20 0.41
AOC3 Q16853 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
HTR1A P08908 3/20 0.39
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C19 P33261 2/20 0.38
HTR2A P28223 2/20 0.38
HTR2B P41595 2/20 0.38
HTR1D P28221 1/20 0.38
HTR1B P28222 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11133752 0.85 CA1 (0.50) ESR1ALDH1A1AOC3CA12CA1
SCHEMBL5604874 0.83 ESR1 (0.46) ESR1ALDH1A1AOC3CA12CA1
SCHEMBL11456399 0.83 ESR1 (0.42) HTR7ESR1ALDH1A1AOC3CA12
Nitrogen SCHEMBL4600860 0.82 ESR1 (0.46) ESR1ALDH1A1AOC3CA12CA1
SCHEMBL24596957 0.80 HTR7 (0.50) HTR7ALDH1A1AOC3CA12CA1
SCHEMBL11415049 0.79 AOC3 (0.44) ALDH1A1AOC3CA12CA1CA2
SCHEMBL11412933 0.79 ACHE (0.43) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL10690592 0.78 CA12 (0.46) ESR1ALDH1A1AOC3CA12CA1
SCHEMBL11674821 0.78 MEN1 (0.44) HTR7ESR1ALDH1A1CYP1A2CYP2D6
SCHEMBL10428522 0.76 CA1 (0.48) HTR7ESR1ALDH1A1AOC3CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4002631-A HEAT-SENSITIVE COLOR FORMERS HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-11 US disclosed