Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.44 |
| ▸ | CA1 | P00915 | 16/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577247 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL1319199 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL8416294 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL6261783 | 0.95 | CA2 (0.50) | CA2CA1CA4KDM4EPOLB | |
| Potassium Ion SCHEMBL410373 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL11770068 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL12805092 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL8342989 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL12805093 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL849086 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065442-A | Pyrolysis compositions from silver salts of polycarboxylic acids | STANDARD OIL COMPANY (US) | 1977-12-27 | — | — | US | disclosed |