Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.44 |
| ▸ | CA1 | P00915 | 16/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577247 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL11770068 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL1319199 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| Potassium Ion SCHEMBL410373 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL12805092 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL8342989 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| Silver SCHEMBL11728702 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL6261783 | 0.95 | CA2 (0.50) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL12805093 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB | |
| SCHEMBL10663236 | 0.95 | CA2 (0.44) | CA2CA1CA4KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613939-B1 | Graphite-free lubricating oil | KYODO YUSHI (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5460737-A | A base oil having a carbohydrate and/or a derivative particle dispersants; lubrication for forging, rolling, drawing, extrusion, tube-making | KYODO YUSHI CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0613939-A2 | Graphite-free lubricating oil | KYODO YUSHI CO., LTD. (JP) | 1994-09-07 | — | — | EP | disclosed |