Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728373 | 0.90 | PPARG (0.38) | MAPTCYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL11729141 | 0.84 | MAPT (0.48) | MAPTCYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL11730769 | 0.82 | PPARG (0.35) | — | |
| SCHEMBL11732630 | 0.82 | POLB (0.40) | ALDH1A1MAPK1LMNATSHR | |
| SCHEMBL11733730 | 0.82 | PPARG (0.33) | MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11731811 | 0.81 | POLB (0.39) | MAPTALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL11729365 | 0.81 | POLB (0.34) | MAPT | |
| SCHEMBL11732066 | 0.81 | PPARG (0.34) | — | |
| SCHEMBL11730361 | 0.81 | PPARG (0.34) | ALDH1A1 | |
| SCHEMBL11725992 | 0.81 | ALDH1A1 (0.34) | MAPTALDH1A1LMNAKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |