Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731811 | 0.93 | POLB (0.39) | POLBPPARGPPARAMAPK1KDM4E | |
| SCHEMBL11729365 | 0.92 | POLB (0.34) | POLBPPARGPPARAKDM4E | |
| SCHEMBL11725992 | 0.92 | ALDH1A1 (0.34) | POLBPPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL11732066 | 0.92 | PPARG (0.34) | POLBPPARGPPARAKDM4ETRPV4 | |
| SCHEMBL11730361 | 0.92 | PPARG (0.34) | POLBPPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL11728265 | 0.91 | PPARG (0.33) | POLBMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL11732689 | 0.91 | PPARG (0.35) | POLBPPARGPPARATSHRMAPK1 | |
| SCHEMBL11733730 | 0.86 | PPARG (0.33) | PPARGPPARAKDM4EALOX5 | |
| SCHEMBL11731641 | 0.85 | KDM4E (0.36) | POLBTSHRKDM4EALDH1A1LMNA | |
| SCHEMBL11730769 | 0.85 | PPARG (0.35) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |