Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.38 |
| ▸ | WNT3A | P56704 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832428 | 0.96 | HPGD (0.42) | L3MBTL1HPGDALDH1A1KDM4EATM | |
| SCHEMBL11733570 | 0.92 | HPGD (0.44) | HPGDATMCTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL11845401 | 0.89 | HPGD (0.43) | HPGDALDH1A1ATMCTNNB1WNT3A | |
| SCHEMBL11836659 | 0.87 | HPGD (0.44) | HPGDALDH1A1KDM4EATMCTNNB1 | |
| SCHEMBL11801974 | 0.85 | MAPT (0.48) | HPGDALDH1A1KDM4EATMCTNNB1 | |
| SCHEMBL11677381 | 0.85 | RAB9A (0.50) | L3MBTL1KDM4ESLC6A4MAPT | |
| SCHEMBL11732446 | 0.83 | CTNNB1 (0.36) | L3MBTL1HPGDALDH1A1KDM4ESLC6A4 | |
| SCHEMBL11797748 | 0.82 | SLC6A4 (0.46) | L3MBTL1HPGDALDH1A1KDM4ESLC6A4 | |
| SCHEMBL11730448 | 0.81 | L3MBTL1 (0.43) | L3MBTL1SLC6A4LMNATP53MAPT | |
| SCHEMBL11678301 | 0.81 | L3MBTL1 (0.49) | L3MBTL1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | claimed |
| US-4008240-A | VIRICIDE | RICHARDSON-MERRELL INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3953602-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-04-27 | — | — | US | disclosed |