Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830691 | 0.86 | CA1 (0.42) | LMNACA1CA2CA9CA12 | |
| SCHEMBL11827666 | 0.85 | LMNA (0.53) | LMNACA1CA2CA9CA12 | |
| SCHEMBL11729595 | 0.83 | LMNA (0.53) | LMNACA1CA2CA9CA12 | |
| SCHEMBL15752460 | 0.79 | LMNA (0.60) | LMNACA1CA2CA9CA12 | |
| SCHEMBL11756263 | 0.79 | LMNA (0.51) | LMNACA1CA2CA9CA12 | |
| SCHEMBL9232630 | 0.78 | CA1 (0.67) | LMNACA1CA2CA9CA12 | |
| SCHEMBL11754838 | 0.78 | LMNA (0.50) | LMNACA1CA2CA9CA12 | |
| SCHEMBL11641060 | 0.76 | LMNA (0.59) | LMNACYP2C19NPC1EGFRERBB2 | |
| SCHEMBL15752503 | 0.74 | LMNA (0.68) | LMNACA1CA2CA9CA12 | |
| SCHEMBL11754945 | 0.74 | LMNA (0.48) | LMNACA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042705-A | 1-Methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |
| US-3962454-A | Bis-(1-alkyl-5-nitro-imidazolyl-2-alkyl)-compounds | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |