Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11151131 | 0.88 | PDE2A (0.45) | PI4KBMAPK14SMN1; SMN2PDE2ARAB9A | |
| SCHEMBL11736204 | 0.87 | PI4KB (0.42) | PI4KBMAPK14ACSS2SMN1; SMN2 | |
| SCHEMBL11255360 | 0.85 | PI4KB (0.44) | PI4KBMAPK14SMN1; SMN2PDE2ARAB9A | |
| SCHEMBL11621025 | 0.85 | PDE2A (0.48) | PI4KBMAPK14SMN1; SMN2PDE2ARAB9A | |
| SCHEMBL11728750 | 0.81 | MEN1 (0.47) | PI4KBMAPK14SMN1; SMN2RAB9A | |
| SCHEMBL11257304 | 0.81 | PDE2A (0.44) | PI4KBSMN1; SMN2PDE2ARAB9ASIRT2 | |
| SCHEMBL11246875 | 0.81 | PI4KB (0.46) | PI4KBMAPK14ACSS2SMN1; SMN2RAB9A | |
| SCHEMBL11262610 | 0.81 | PI4KB (0.48) | PI4KBMAPK14ACSS2SMN1; SMN2RAB9A | |
| SCHEMBL11625701 | 0.80 | MAPK14 (0.44) | PI4KBMAPK14ACSS2SMN1; SMN2 | |
| SCHEMBL11147527 | 0.80 | PI4KB (0.43) | PI4KBMAPK14ACSS2SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | claimed |