Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11151131 | 0.88 | PDE2A (0.45) | PI4KBMAPK14CA2SMN1; SMN2PDE2A | |
| SCHEMBL11728750 | 0.86 | MEN1 (0.47) | PI4KBMAPK14JMJD6CA2SMN1; SMN2 | |
| SCHEMBL11730587 | 0.85 | PI4KB (0.39) | PI4KBMAPK14SMN1; SMN2PDE2ARAB9A | |
| SCHEMBL11621025 | 0.85 | PDE2A (0.48) | PI4KBMAPK14CA2SMN1; SMN2PDE2A | |
| SCHEMBL11248780 | 0.84 | NOD1 (0.38) | PI4KBJMJD6ACHESMN1; SMN2NPC1 | |
| SCHEMBL11736204 | 0.82 | PI4KB (0.42) | PI4KBMAPK14CA2SMN1; SMN2CYP3A4 | |
| SCHEMBL11257304 | 0.81 | PDE2A (0.44) | PI4KBCA2SMN1; SMN2PDE2ANPC1 | |
| SCHEMBL11246875 | 0.81 | PI4KB (0.46) | PI4KBMAPK14SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11262610 | 0.81 | PI4KB (0.48) | PI4KBMAPK14SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11625701 | 0.80 | MAPK14 (0.44) | PI4KBMAPK14CA2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |