Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730587 | 0.87 | PI4KB (0.39) | PI4KBMAPK14SMN1; SMN2ACSS2 | |
| SCHEMBL11622008 | 0.85 | PI4KB (0.59) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11728750 | 0.85 | MEN1 (0.47) | PI4KBMAPK14CA12CA1CA2 | |
| SCHEMBL11151131 | 0.85 | PDE2A (0.45) | PI4KBMAPK14CA12CA1CA2 | |
| SCHEMBL11262610 | 0.84 | PI4KB (0.48) | PI4KBMAPK14SMN1; SMN2ACSS2NOD1 | |
| SCHEMBL11246875 | 0.84 | PI4KB (0.46) | PI4KBMAPK14SMN1; SMN2ACSS2BRD4 | |
| SCHEMBL11621025 | 0.82 | PDE2A (0.48) | PI4KBMAPK14CA12CA1CA2 | |
| SCHEMBL11255360 | 0.82 | PI4KB (0.44) | PI4KBMAPK14CA2SMN1; SMN2CYP3A4 | |
| SCHEMBL11734410 | 0.81 | MAPK14 (0.41) | PI4KBMAPK14SMN1; SMN2CYP3A4 | |
| SCHEMBL11625701 | 0.81 | MAPK14 (0.44) | PI4KBMAPK14CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | claimed |