Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730159 | 0.92 | TBXA2R (0.45) | KMT2A | |
| SCHEMBL11722942 | 0.92 | TSHR (0.44) | ADRB2 | |
| SCHEMBL11725475 | 0.91 | MAPK1 (0.46) | — | |
| SCHEMBL11726905 | 0.91 | NPC1 (0.40) | — | |
| SCHEMBL11730044 | 0.91 | KDM4E (0.39) | KMT2A | |
| SCHEMBL11730449 | 0.91 | CYSLTR2 (0.35) | — | |
| SCHEMBL11730754 | 0.91 | LTA4H (0.45) | — | |
| SCHEMBL11732450 | 0.90 | PRMT5 (0.36) | — | |
| SCHEMBL11733944 | 0.90 | KMT2A (0.42) | SMN1; SMN2KMT2A | |
| SCHEMBL11728921 | 0.90 | ADRB2 (0.46) | ADRB2ADRB1SMN1; SMN2HPGDADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |