Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614426 | 0.83 | LMNA (0.44) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL23036042 | 0.81 | TSHR (0.41) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL5158616 | 0.75 | USP2 (0.40) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL14759689 | 0.73 | USP2 (0.39) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL9392455 | 0.73 | LMNA (0.46) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL13518649 | 0.73 | USP2 (0.33) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL8864832 | 0.72 | TDP1 (0.40) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL2933990 | 0.70 | PDE4A (0.54) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL5807432 | 0.69 | USP2 (0.41) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL3624845 | 0.69 | USP2 (0.39) | USP2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801570-B1 | FORMULATIONS AND METHODS FOR REDUCING SKIN IRRITATION | COSMEDERM TECHNOLOGIES (US) | 2004-12-08 | — | — | EP | claimed |
| EP-1136065-B1 | Formulations and methods for reducing skin irritation | COSMEDERM TECHNOLOGIES (US) | 2004-11-24 | — | — | EP | claimed |
| EP-0801554-B1 | FORMULATIONS AND METHODS FOR REDUCING SKIN IRRITATION | COSMEDERM TECHNOLOGIES (US) | 2003-04-16 | — | — | EP | claimed |
| EP-0806933-B1 | FORMULATIONS AND METHODS FOR REDUCING SKIN IRRITATION | COSMEDERM TECHNOLOGIES (US) | 2002-08-28 | — | — | EP | claimed |
| US-6267948-B1 | ADMINISTERING TO MAMMALIAN SKIN, HAIR, WOOL OR FUR DERMATOLOGICAL FORMULATION CONTAINING MELANOGENESIS STIMULATING AGENT WHICH STIMULATES MELANOGENESIS IN MELANOCYTES AND HYDROXY ACID TO ENHANCE MELANOGENESIS | APPLIED GENETICS INCORPORATED DERMATICS | 2001-07-31 | — | — | US | claimed |
| WO-1999051198-A1 | DERMATOLOGICAL FORMULATIONS AND METHODS | CODON PHARMACEUTICALS, INC. (US) | 1999-10-14 | — | — | WO | claimed |
| US-5925366-A | PERMEATION/BINDING AGENT, THIO CROSSLINKING AGENT, AND CHELATE COMPOUND | REVLON CONSUMER PRODUCTS CORPORATION (US) | 1999-07-20 | — | — | US | claimed |
| US-5785959-A | MIXTURE CONTAINING A PERMEATION/BINDING AGENT, A THIO CROSSLINKING AGENT, A CHELATING AGENT, WATER AND AN OIL | REVLON CONSUMER PRODUCTS CORPORATION (US) | 1998-07-28 | — | — | US | claimed |
| WO-1998006376-A1 | NAIL STRENGTHENING COMPOSITIONS AND A METHOD FOR STRENGTHENING NAILS | REVLON CONSUMER PRODUCTS CORPORATION (US) | 1998-02-19 | — | — | WO | claimed |
| EP-0338565-B1 | N-Alkoxyalkylamides of hydroxyacids and skin treating compositions therewith | REVLON CONSUMER PROD CORP (US) | 1994-08-10 | — | — | EP | claimed |
| US-5139771-A | Hydrolyzed grain product, seaweed derivative, water | REVLON, INC. (US) | 1992-08-18 | — | — | US | claimed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-10334929-B2 | Hair product application device | The Pro-Motion Group, LLC (US) | 2019-07-02 | — | — | US | disclosed |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2019-06-13 | — | — | US | disclosed |
| US-5306489-A | Hair care products containing N-alkoxyalkylamides | REVLON CONSUMER PRODUCTS CORPORATION (US) | 1994-04-26 | — | — | US | disclosed |
| EP-0580453-A2 | Hair-care compositions containing N-alkoxyalkylamides | Revlon Consumer Products Corporation (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5139771-A | Hydrolyzed grain product, seaweed derivative, water | REVLON, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| US-5102654-A | For hydrating human nails | REVLON, INC. (US) | 1992-04-07 | — | — | US | disclosed |
| WO-1991000083-A1 | SKIN CARE PREPARATION | REVLON, INC. (US) | 1991-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | USP2 4377/4885SLCO1B1 3219/4885LMNA 3784/4885 |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | USP2 4285/4885SLCO1B1 3227/4885LMNA 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.