Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348479 | 0.91 | SRD5A1 (0.40) | HTR6ESR1ESR2 | |
| SCHEMBL31028103 | 0.91 | SRD5A1 (0.40) | HTR6ESR1ESR2 | |
| SCHEMBL12048682 | 0.91 | SRD5A1 (0.40) | HTR6ESR1ESR2 | |
| SCHEMBL31028096 | 0.88 | KDM4C (0.44) | HTR6 | |
| SCHEMBL24593561 | 0.80 | HTR6 (0.48) | HTR6ESR1ESR2 | |
| SCHEMBL24859371 | 0.80 | HTR6 (0.48) | HTR6ESR1ESR2 | |
| SCHEMBL10175564 | 0.78 | SIGMAR1 (0.53) | HTR6 | |
| Hydrochloric Acid SCHEMBL9523523 | 0.78 | HTR6 (0.64) | HTR6ESR1ESR2 | |
| SCHEMBL31028086 | 0.78 | HTR2C (0.40) | ESR1ESR2 | |
| SCHEMBL5477585 | 0.78 | HTR6 (0.47) | HTR6ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065569-A | Use of 2-imidazolines as hypoglycemic agents | SCHERING CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-3992403-A | 2-Imidazolines and their use as hypoglycemic agents | SCHERING CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |