Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EPOR | P19235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11732630 | 0.91 | POLB (0.40) | PPARGPPARAMAPK1L3MBTL1TSHR | |
| SCHEMBL11731811 | 0.90 | POLB (0.39) | PPARGPPARAMAPK1KDM4EALDH1A1 | |
| SCHEMBL11730361 | 0.90 | PPARG (0.34) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL11725992 | 0.90 | ALDH1A1 (0.34) | PPARGPPARAKDM4EALDH1A1POLB | |
| SCHEMBL11732066 | 0.90 | PPARG (0.34) | PPARGPPARAKDM4EPOLB | |
| SCHEMBL11729365 | 0.90 | POLB (0.34) | PPARGPPARAKDM4EPOLB | |
| SCHEMBL11728265 | 0.89 | PPARG (0.33) | PPARGPPARAPOLB | |
| SCHEMBL11732679 | 0.85 | MAPK1 (0.38) | PPARGPPARAMAPK1L3MBTL1TSHR | |
| SCHEMBL11733730 | 0.84 | PPARG (0.33) | PPARGPPARACA12CA2CA9 | |
| SCHEMBL11731641 | 0.83 | KDM4E (0.36) | TSHRKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |