SCHEMBL1173283

SCHEMBL1173283

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(=O)c5cccc(Cl)c5Cl)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.67
CYP46A1 Q9Y6A2 2/20 0.65
OSBP P22059 3/20 0.61
USP2 O75604 2/20 0.61
RORC P51449 2/20 0.61
LMNA P02545 1/20 0.61
ABCB1 P08183 1/20 0.61
OSBP2 Q969R2 1/20 0.61
NR1H3 Q13133 4/20 0.55
NPC1L1 Q9UHC9 2/20 0.54
NPC1 O15118 1/20 0.54
GBA1 P04062 2/20 0.53
UGCG Q16739 2/20 0.53
GBA2 Q9HCG7 2/20 0.53
CYP1A2 P05177 1/20 0.53
GRIN1 Q05586 1/20 0.53
GRIN2A Q12879 1/20 0.53
PLA2G2A P14555 1/20 0.52
EPHA2 P29317 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28354580 1.00 POLA1 (0.67) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL1173285 1.00 POLA1 (0.67) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL1296893 0.92 POLA1 (0.75) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL19991732 0.90 POLA1 (0.67) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL2979168 0.89 POLA1 (0.69) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL1296890 0.89 POLA1 (0.73) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL2979167 0.89 POLA1 (0.69) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL4437346 0.89 POLA1 (0.73) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL9186858 0.89 POLA1 (0.69) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL1296888 0.89 POLA1 (0.73) POLA1CYP46A1OSBPUSP2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009079546-A1 CHOLESTERIC LIQUID CRYSTAL COLORING COMPOSITIONS AND ARTICLES PRODUCED THEREFROM AVON PRODUCTS, INC. (US) 2009-06-25 WO claimed
US-20220162581-A1 Solution Stable Enzyme Composition AB ENZYMES FINLAND OY (FI) 2022-05-26 US disclosed
EP-3953459-A1 SOLUTION STABLE ENZYME COMPOSITION AB Enzymes Oy (FI) 2022-02-16 EP disclosed
WO-2020208296-A1 SOLUTION STABLE ENZYME COMPOSITION AB ENZYMES OY (FI) 2020-10-15 WO disclosed
EP-3722418-A1 SOLUTION STABLE ENZYME COMPOSITION AB Enzymes Oy (FI) 2020-10-14 EP disclosed
EP-1256336-B1 Two-phase gel composition PENRECO (US) 2016-10-19 EP disclosed
US-9339446-B2 Gel composition CALUMET PENRECO, LLC (US) 2016-05-17 US disclosed
US-20110045983-A1 Gel composition WILMINGTON TRUST, NATIONAL ASSOCIATION 2011-02-24 US disclosed
US-20090232753-A1 Gel compositions HEALY LIN LU 2009-09-17 US disclosed
WO-2009079546-A1 CHOLESTERIC LIQUID CRYSTAL COLORING COMPOSITIONS AND ARTICLES PRODUCED THEREFROM AVON PRODUCTS, INC. (US) 2009-06-25 WO disclosed
EP-1141111-B1 GEL COMPOSITIONS PENRECO (US) 2005-08-03 EP disclosed
US-6881776-B2 Gel compositions PENRECO (US) 2005-04-19 US disclosed
US-20050004274-A1 Gel compositions HEALY LIN LU (US) 2005-01-06 US disclosed
EP-1256336-A2 Two-phase gel composition Penreco (US) 2002-11-13 EP disclosed
US-20020055562-A1 Gel compositions WILMINGTON TRUST, NATIONAL ASSOCIATION 2002-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110045983-A1 Gel composition PGR, COPE, PTGER1 POLA1 1495/4885CYP46A1 499/4885OSBP 810/4885
US-20090232753-A1 Gel compositions PGR, COPE, PTGER1 POLA1 1637/4885CYP46A1 579/4885OSBP 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.