Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | OGT | O15294 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730520 | 0.91 | FOLH1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL10674321 | 0.90 | SMN1; SMN2 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10759071 | 0.90 | SMN1; SMN2 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11729486 | 0.89 | CACNA2D1 (0.35) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11736974 | 0.85 | MAPT (0.36) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11728164 | 0.84 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL11734433 | 0.83 | SMN1; SMN2 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11696848 | 0.82 | LMNA (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11459390 | 0.81 | — | — | |
| SCHEMBL10794420 | 0.81 | GPR132 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009272-A | ANTIBIOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-22 | — | — | US | disclosed |