Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.72 |
| ▸ | PPARA | Q07869 | 8/20 | 0.67 |
| ▸ | PPARD | Q03181 | 3/20 | 0.67 |
| ▸ | RXRA | P19793 | 1/20 | 0.61 |
| ▸ | RXRB | P28702 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729678 | 0.88 | PPARG (0.91) | PPARGPPARAPPARD | |
| SCHEMBL5795674 | 0.86 | PPARG (0.83) | PPARGPPARAPPARD | |
| SCHEMBL2131476 | 0.86 | PPARA (0.67) | PPARGPPARAPPARD | |
| SCHEMBL11733799 | 0.85 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL11734207 | 0.85 | PPARA (0.73) | PPARGPPARAPPARD | |
| SCHEMBL21991803 | 0.85 | PPARA (0.73) | PPARGPPARAPPARD | |
| SCHEMBL11737620 | 0.85 | PPARG (0.72) | PPARGPPARAPPARDRXRARXRB | |
| SCHEMBL21991794 | 0.83 | PPARA (0.77) | PPARGPPARAPPARD | |
| SCHEMBL13821685 | 0.78 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL2352150 | 0.78 | RXRA (0.46) | PPARGPPARAPPARDRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3968143-A | Phenoxypropionic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-07-06 | — | — | US | claimed |
| US-4039683-A | PHENOXYPROPIONIC ACID DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-08-02 | — | — | US | disclosed |
| US-3968143-A | Phenoxypropionic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-07-06 | — | — | US | disclosed |