SCHEMBL2352150

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL883026	0.83	SLC16A3 (0.55)	PPARGPPARASLC16A3SLC16A1MCTS1
	SCHEMBL2716903	0.83	CYP3A4 (0.44)	RXRARXRBAPPCYP3A4IDO1
	SCHEMBL8935661	0.82	SLC16A3 (0.46)	PPARGPPARASLC16A3SLC16A1MCTS1
	SCHEMBL2215266	0.82	RXRA (0.46)	RXRARXRBPPARGPPARASLC16A3
	SCHEMBL31377393	0.81	NPC1 (0.53)	PPARGPPARASLC16A3SLC16A1MCTS1
	SCHEMBL2221138	0.81	SLC16A3 (0.53)	PPARGSLC16A3SLC16A1MCTS1IDO1
	SCHEMBL8935846	0.79	PPARA (0.50)	PPARGPPARAIDO1PPARD
	Clobuzarit SCHEMBL187456	0.78	SLC16A3 (0.62)	PPARGPPARASLC16A3SLC16A1MCTS1
	SCHEMBL11734564	0.78	PPARG (0.72)	RXRARXRBPPARGPPARAAPP
	SCHEMBL11957480	0.77	CYP3A4 (0.52)	APPCYP3A4IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.