Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654722 | 0.81 | GCK (0.46) | GCKKMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL11730615 | 0.81 | LMNA (0.59) | GCKKMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL2668152 | 0.76 | GCK (0.44) | GCKKMT2ALMNAALDH1A1 | |
| SCHEMBL10395347 | 0.75 | GCK (0.45) | GCKKMT2ALMNAALDH1A1CHRM5 | |
| SCHEMBL191452 | 0.74 | GCK (0.47) | GCKKMT2ALMNAALDH1A1CHRM5 | |
| SCHEMBL3531433 | 0.74 | GCK (0.52) | GCKKMT2ALMNAALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL10395339 | 0.74 | LMNA (0.46) | GCKKMT2ALMNAALDH1A1CHRM5 | |
| SCHEMBL10395769 | 0.74 | KMT2A (0.62) | GCKKMT2ALMNAALDH1A1NPC1 | |
| SCHEMBL5654395 | 0.72 | ALDH1A1 (0.59) | GCKKMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL4251207 | 0.71 | GCK (0.44) | GCKKMT2ALMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005202-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-3935209-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-01-27 | — | — | US | disclosed |