Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10244710 | 0.81 | ALDH1A1 (0.42) | GRM5ALDH1A1KMT2ARAB9AMAPT | |
| SCHEMBL13642170 | 0.80 | GRM5 (0.49) | GRM5KMT2ASMN1; SMN2HTT | |
| SCHEMBL13641764 | 0.80 | GRM5 (0.49) | GRM5KMT2ASMN1; SMN2HTT | |
| SCHEMBL5021798 | 0.80 | GRM5 (0.58) | GRM5 | |
| SCHEMBL4559488 | 0.77 | GRM5 (0.73) | GRM5 | |
| SCHEMBL5022046 | 0.77 | GRM5 (0.73) | GRM5 | |
| SCHEMBL5021666 | 0.76 | GRM5 (0.60) | GRM5ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5021667 | 0.76 | GRM5 (0.60) | GRM5ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5022052 | 0.72 | GRM5 (0.50) | GRM5 | |
| SCHEMBL5022051 | 0.72 | GRM5 (0.50) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059447-A | Photographic material containing oxazolinone-2 couplers | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |