Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064741 | 0.78 | CRBN (0.42) | CRBNHTTKMT2AMEN1CASP3 | |
| SCHEMBL6063987 | 0.71 | CRBN (0.46) | CRBNHTTKMT2AMEN1CASP3 | |
| SCHEMBL3231672 | 0.71 | CRBN (0.41) | CRBNHTTKMT2AMEN1CASP3 | |
| SCHEMBL345503 | 0.68 | CRBN (0.38) | CRBNHTTKMT2AMEN1CASP3 | |
| SCHEMBL31140232 | 0.67 | HTT (0.69) | CRBNHTTKMT2AMEN1RAB9A | |
| SCHEMBL11004284 | 0.67 | CRBN (0.37) | CRBNHTTKMT2AMEN1CASP3 | |
| SCHEMBL10480507 | 0.62 | CRBN (0.41) | CRBNHTTKMT2AMEN1ALDH1A1 | |
| Creatinine SCHEMBL7735944 | 0.61 | CRBN (0.50) | CRBNKMT2AMEN1NPC1GAA | |
| SCHEMBL16549938 | 0.60 | INMT (0.48) | HTTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL8345781 | 0.60 | TSHR (0.39) | CRBNKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049650-A | 1-[[[5-(Substituted phenyl)-2-oxazolyl]methylene]amino]-2,4-imidazolidinediones | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-09-20 | — | — | US | disclosed |