Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 3/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11591339 | 0.82 | BRD4 (0.56) | HTTALDH1A1KMT2ABRD4HPGD | |
| SCHEMBL9375233 | 0.82 | HTT (1.00) | HTTALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL10997891 | 0.79 | PKM (0.69) | HTTALDH1A1HPGDPKMSIGMAR1 | |
| SCHEMBL8417169 | 0.76 | ALDH1A1 (0.54) | HTTALDH1A1KMT2AHPGDRAB9A | |
| SCHEMBL9381334 | 0.75 | HTT (0.71) | HTTALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL3346307 | 0.74 | KMT2A (0.54) | HTTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL2064741 | 0.73 | CRBN (0.42) | HTTALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL30063016 | 0.72 | ALDH1A1 (0.55) | HTTALDH1A1KMT2AHPGDRAB9A | |
| SCHEMBL18660612 | 0.72 | HTT (0.80) | HTTALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL6972083 | 0.71 | HTT (0.79) | HTTALDH1A1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032662-B | Compounds that interact with the RAS superfamily for the treatment of cancer, inflammatory diseases, RAS proteinopathies and fibrotic diseases | 尚医治疗有限责任公司 | 2024-10-15 | — | — | CN | disclosed |