Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTGFR | P43088 | 3/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728925 | 0.90 | TBXA2R (0.45) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11725299 | 0.89 | PTGFR (0.43) | PTGFRTBXA2RPTGER1PTGER3PTGDR | |
| SCHEMBL11730106 | 0.89 | TBXA2R (0.53) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11729589 | 0.89 | TBXA2R (0.44) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11850231 | 0.89 | PTGFR (0.58) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11726287 | 0.89 | TBXA2R (0.44) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11728039 | 0.89 | TBXA2R (0.46) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11722951 | 0.88 | TSHR (0.46) | TSHRMAPK1KDM4EALDH1A1BCHE | |
| SCHEMBL11725189 | 0.88 | TBXA2R (0.44) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| Water SCHEMBL11730258 | 0.88 | PTGFR (0.57) | PTGFRTBXA2RPTGER1PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |