Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730106 | 0.91 | TBXA2R (0.53) | PTGFRTBXA2RPTGER1PTGER3PTGDR | |
| SCHEMBL11729925 | 0.90 | LTA4H (0.43) | PTGFRTBXA2RPTGER1PTGER3PTGDR | |
| SCHEMBL11735558 | 0.89 | TSHR (0.47) | PTGFRTBXA2RPTGER1PTGER3PTGDR | |
| SCHEMBL11852601 | 0.87 | ALOX15 (0.40) | CA1CA2CA4CA7CA9 | |
| SCHEMBL11729091 | 0.83 | TBXA2R (0.39) | PTGFRTBXA2RPTGER1PTGER3PTGDR | |
| SCHEMBL11516147 | 0.83 | ALDH1A1 (0.44) | PTGFRTBXA2RPTGER1PTGER3PTGDR | |
| SCHEMBL11728925 | 0.83 | TBXA2R (0.45) | PTGFRTBXA2RPTGER1PTGER3PTGDR | |
| SCHEMBL11728039 | 0.82 | TBXA2R (0.46) | PTGFRTBXA2RPTGER1PTGER3PTGDR | |
| SCHEMBL11729971 | 0.82 | TBXAS1 (0.42) | PTGFRTBXA2RPTGER1PTGER3PTGDR | |
| SCHEMBL11726287 | 0.82 | TBXA2R (0.44) | PTGFRTBXA2RPTGER1PTGER3PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | claimed |
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |