Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11736642 | 0.93 | MAOB (0.49) | MAOBTDP1L3MBTL1ACHEBCHE | |
| SCHEMBL11741242 | 0.89 | MAOB (0.62) | MAOBACHEBCHE | |
| SCHEMBL11734544 | 0.85 | MAOB (0.55) | MAOBACHEBCHEPGRCYP1A2 | |
| SCHEMBL11739072 | 0.84 | ACHE (0.47) | MAOBACHEBCHEPGRCYP1A2 | |
| SCHEMBL11734596 | 0.82 | MAOB (0.53) | MAOBACHEPGRCYP1A2CYP3A4 | |
| SCHEMBL11639312 | 0.82 | KMT2A (0.57) | MAOBPGRCYP1A2CYP3A4TSHR | |
| SCHEMBL11735366 | 0.79 | ACHE (0.46) | TDP1L3MBTL1ACHEPGRCYP1A2 | |
| SCHEMBL11737697 | 0.77 | MAOB (0.51) | MAOBTDP1PGRCYP1A2CYP3A4 | |
| SCHEMBL11737347 | 0.77 | CYP1A2 (0.53) | TDP1PGRCYP1A2CYP3A4TSHR | |
| SCHEMBL11737018 | 0.76 | CYP1A2 (0.49) | ACHEPGRCYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031219-A | ANTIARRHYTHYMICS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-06-21 | — | — | US | disclosed |