Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | PGR | P06401 | 10/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741201 | 0.95 | MAOB (0.47) | MAOBPGRADRA1ACYP1A2CYP3A4 | |
| SCHEMBL11734596 | 0.92 | MAOB (0.53) | MAOBPGRADRA1ACYP1A2CYP3A4 | |
| SCHEMBL11738968 | 0.87 | TDP1 (0.64) | MAOBPGRADRA1ACYP1A2CYP3A4 | |
| SCHEMBL11738951 | 0.87 | CYP1A2 (0.53) | MAOBPGRADRA1ACYP1A2CYP3A4 | |
| SCHEMBL11639312 | 0.86 | KMT2A (0.57) | MAOBPGRADRA1ACYP1A2CYP3A4 | |
| SCHEMBL11735706 | 0.83 | TDP1 (0.59) | MAOBPGRADRA1ACYP1A2CYP3A4 | |
| SCHEMBL11735486 | 0.83 | TDP1 (0.59) | MAOBPGRADRA1ACYP1A2CYP3A4 | |
| SCHEMBL11741136 | 0.82 | PGR (0.53) | PGRADRA1ACYP1A2CYP3A4TSHR | |
| SCHEMBL11738541 | 0.82 | MAOB (0.44) | MAOBPGRADRA1ACYP1A2CYP3A4 | |
| SCHEMBL11734544 | 0.81 | MAOB (0.55) | MAOBPGRADRA1ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031219-A | ANTIARRHYTHYMICS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-06-21 | — | — | US | disclosed |