Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11732779 | 0.90 | TP53 (0.35) | SMN1; SMN2TP53MAPTKMT2AKDM4E | |
| SCHEMBL11773941 | 0.90 | ALPL (0.36) | SMN1; SMN2ALPLTP53MAPTKDM4E | |
| SCHEMBL11737536 | 0.90 | MAPT (0.38) | SMN1; SMN2TP53MAPTKDM4ENPC1 | |
| SCHEMBL11730627 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2ALPLTP53MAPTKMT2A | |
| SCHEMBL11739172 | 0.87 | ALDH1A1 (0.36) | SMN1; SMN2TP53MAPTKDM4ENPC1 | |
| SCHEMBL11741869 | 0.87 | TP53 (0.40) | SMN1; SMN2TP53MAPTKDM4ETSHR | |
| SCHEMBL11735866 | 0.86 | TP53 (0.37) | SMN1; SMN2TP53MAPTKMT2AKDM4E | |
| SCHEMBL11739842 | 0.86 | TP53 (0.39) | SMN1; SMN2TP53MAPTKMT2ANPC1 | |
| SCHEMBL11733154 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53MAPTKDM4ENPC1 | |
| SCHEMBL11735715 | 0.85 | MAPT (0.40) | SMN1; SMN2TP53MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041163-A | N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents | PFIZER INC. (US) | 1977-08-09 | — | — | US | disclosed |