Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873032 | 0.86 | AKR1C3 (0.61) | SMN1; SMN2RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL8285571 | 0.86 | KMT2A (0.59) | HPGDSMN1; SMN2GAARAB9ALMNA | |
| SCHEMBL18893559 | 0.85 | MEN1 (0.54) | KMT2AMEN1 | |
| SCHEMBL11115690 | 0.83 | KMT2A (0.61) | HPGDSMN1; SMN2GAARAB9ALMNA | |
| SCHEMBL11108977 | 0.83 | KMT2A (0.53) | HPGDSMN1; SMN2GAARAB9ALMNA | |
| SCHEMBL25722908 | 0.82 | MAPT (0.75) | HPGDSMN1; SMN2GAARAB9ALMNA | |
| SCHEMBL3685150 | 0.82 | HTT (0.54) | HPGDSMN1; SMN2GAARAB9AKMT2A | |
| SCHEMBL27536284 | 0.82 | HPGD (0.53) | HPGDSMN1; SMN2GAARAB9AKMT2A | |
| SCHEMBL11113486 | 0.82 | KMT2A (0.51) | HPGDSMN1; SMN2GAARAB9ALMNA | |
| SCHEMBL10145068 | 0.81 | RAB9A (0.61) | HPGDSMN1; SMN2RAB9ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053470-A | BACTERICIDES, ANTIBIOTICS | PARKE, DAVIS & COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-3954734-A | PENICILLIN AND CEPHALOSPORIN TYPE | PARKE, DAVIS & COMPANY | 1976-05-04 | — | — | US | disclosed |