Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686732 | 0.86 | AKR1C3 (0.58) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11115690 | 0.86 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2HPGDGAA | |
| SCHEMBL11108977 | 0.86 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2HPGDGAA | |
| SCHEMBL8686770 | 0.84 | HTR7 (0.55) | KMT2AMEN1 | |
| SCHEMBL11735992 | 0.82 | HPGD (0.59) | KMT2AMEN1SMN1; SMN2HPGDGAA | |
| SCHEMBL11935015 | 0.82 | SMN1; SMN2 (0.49) | KMT2AMEN1SMN1; SMN2HPGDGAA | |
| SCHEMBL11118147 | 0.81 | RAB9A (0.56) | KMT2AMEN1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL13033166 | 0.81 | ALDH1A1 (0.55) | KMT2AMEN1SMN1; SMN2HPGDGAA | |
| SCHEMBL2645244 | 0.80 | KMT2A (0.66) | KMT2AMEN1SMN1; SMN2HPGDGAA | |
| SCHEMBL27861904 | 0.79 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0058868-A1 | Derivatives of tetrahydropyrimidinon, process for their preparation and herbicides containing those derivatives as active products | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-09-01 | — | — | EP | disclosed |